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Hyperthermia applies controlled heat to a selected tissue region.
Key points
- Energy delivery
- Local heating
- Monitoring
Understanding the approach
Focus the heat
A treatment device delivers energy to a defined area.
Monitor tissue
Temperature control helps manage effects on the target and nearby tissue.
Plan the combination
Some forms are used with other cancer treatments in specialist settings.
Evidence & context
Benefits and risks depend on the device, cancer and treatment plan. Burns, discomfort and tissue injury can occur.
How Optimal Tumor Heating at 44°C - 46°C (110° - 116°F) Can Improve Cancer Treatment
The Thermofield® Noninvasive Tumor Heating System is a groundbreaking medical device with enormous potential to improve cancer treatment. By harnessing the power of heat, this cutting-edge system can safely elevate tumor temperatures to levels never before possible with external heating devices, all while ensuring the utmost protection for the skin. Skin surface temperature is 4°C lower than the internal temperature and thus is tolerable for the patient.
Peer-reviewed research has demonstrated that temperatures above 45°C (114°F) effectively destroy cancer cells and stimulate a significant increase in heat shock proteins (HSPs) expressed on the cell surface.[1] This remarkable surge in extracellular HSPs serves as an antigen, compelling the immune system to launch a persistent attack against the tumor. Moreover, it has been observed that optimal heat can kill cancer cells, with 96% of melanoma cells eradicated in-vitro in 24 hours after just 11 minutes of direct heating.[1] Alongside its ability to kill cancer cells and trigger a potent immune response, the continuous heat stress applied to the tumor tends to collapse its blood supply, further inhibiting its ability to survive.
Additional Benefits Associated with Heating the Tumor
✔︎ Better outcomes with no additional toxicity to the patient.
✔︎ Kills cancer stem cells that are highly resistant to conventional treatments.
✔︎ Palliatescancer pain by reducing pressure on adjacent nerve tissue.
✔︎ Enhances the uptake and biodistribution of drugs and natural compounds used to treat cancer.
✔︎ Reverses drug resistance.
✔︎ Disrupts the tumor microenvironment weakening cancer cells and making them more susceptible to anti-cancer therapy.
Hyperthermia has a proven additive or synergistic effect with the following cancer therapies
Mistletoe TherapyQuercetin
EGCG
IV Vitamin CNano-sized Curcumin
Hydrogen Gas
Iron Dextran
Photodynamic Therapy
HBOTChemotherapy
Immunotherapy